Is it possible to predict neurosensory alterations in impacted lower third molar removal based on preoperative imaging procedures? A prospective cohort study / ¿Es posible predecir alteraciones neurosensoriales en la extracción del tercer molar inferior impactado basándose en procedimientos de imagen preoperatorios? Un estudio de cohorte prospectivo

Background: Surgical extraction of the lower third molar (LTM) may trigger neurosensory injury of the inferioralveolar nerve, making extraction a real challenge. This study set out to assess whether is it possible to predictneurosensory alterations from preoperative imaging.Material and Methods: A total of 99 patients underwent 124 impacted lower third molar (ILTM) surgeries. Priorto surgery, panoramic and CBCT images were evaluated in an attempt to predict a neurosensory disturbance.Preoperative data (ILTM position, panoramic radiograph signs, inferior alveolar nerve (IAN) location and its con-tact with the ILTM roots) and intra/postoperative findings (extraction difficulty and sensitivity alterations) wererecorded. Descriptive and bivariate data analysis was performed. Statistical comparison applied the chi-squaretest, Fisher test, and one-way ANOVA test. Statistical significance was established with a confidence interval (CI)of 95%.Results: In 4.03% of cases, patients experienced neurosensory alterations. Of 124 ILTM positions in panoramicradiographs, 76 cases were considered to exhibit a potential neurosensory risk as they presented two or more typesof superimposed relationships between ILTM and mandibular canal. Of these, alterations were reported in onlythree cases (3.95%). Of the 48 remaining ILTM images presenting only one sign, neurosensory alterations wereobserved in two cases (4.17%). No permanent alterations were recorded in any of the five cases observed.Conclusions: Within the limitations of the present study, prediction of neurosensory alterations prior to ILTMextraction by means of preoperative imaging did not show a significant statistical correlation with post-surgicalincidence. Nevertheless, interruption of the canal´s white line (ICWL) or a diversion of the canal (DC) may predictan increased risk of IAN injury.(AU)

Effect of the buccal fat pad in the prevention of zygomatic implant surgery postoperative complications: A pilot study

Background: Zygomatic implants have been used to treat severe atrophy maxilla. Since its description, the technique has been improved in order to reduce patient morbidity as well as prosthesis rehabilitation time. Despite the improvements in the procedure, zygomatic implant treatments still have complications related to the peri-implant soft-tissue; a probing depth greater than 6 millimeter (mm) and a prevalence of bleeding on probing of 45% have been described. The mobilization of the buccal fat has been used to manage different oral and maxillofacial soft-tissue pathologies. The aim of this study was to assess whether the buccal fat pad might prevent mucosal dehiscence and avoid potential postoperative complications when is placed covering the body part of the zygomatic implants. Material and methods: In this pilot study, 7 patients were enrolled and a total of 28 zygomatic implants were placed and evaluated during a 12-month follow-up period. Surgical sites were randomly divided into two groups before implant placement: control group (A; in which no buccal fat pad was applied) and experimental group (B). Peri-implant soft tissue thickness difference, pain using a Visual Analog Scale (VAS), swelling, hematoma, buccal soft tissue healing and sinusitis, were evaluated. The implant survival rate was determined according the Aparicio success criteria and compared between the control and experimental procedure. Results: A nonstatistical difference was found between groups regarding to pain. The experimental group showed higher soft-tissues thickness (p= 0.03) and the implant survival rate was 100% in both groups. Conclusions: The mobilization of the buccal fat pad to cover the body of the zygomatic implants increases peri-implant soft-tissue thickness, without increasing the postoperative pain. (AU)

Plasma rich in growth factors (PRGF) and leukocyte-platelet rich fibrin (L-PRF): comparative release of growth factors and biological effect on osteoblasts.

PURPOSE: To compare the release of platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF-I) and interleukin 1ß (IL-1ß) of plasma rich in growth factors (PRGF) and leucocyte platelet-rich fibrin (L-PRF) and to evaluate their biological implication in osteoblasts. METHODS: Blood from 3 healthy volunteers was processed into PRGF, immediate L-PRF (L-PRF 0') and L-PRF 30 min after collection (L-PRF-30') and a control group. Growth factors release were analyzed at 7 times by ELISA. Cell proliferation, collagen-I synthesis and alkaline phosphatase activity were assessed in primary cultures of human osteoblasts. RESULTS: A slower controlled release of IGF-I, VEGF and PDGF was observed in the PRGF group at day 14. A higher synthesis of type I collagen was also quantified in PRGF. L-PRF released significantly higher amounts of IL-1ß, that was almost absent in the PRGF. CONCLUSIONS: The addition of leukocytes dramatically increases the secretion of proinflammatory cytokines, which are likely to negatively influence the synthesis of type I collagen and alkaline phosphatase (ALP) by osteoblasts.

Patient-reported outcomes in patients with severe maxillary bone atrophy restored with zygomatic implant-supported complete dental prostheses: a systematic review.

Introduction and Objective: Zygomatic implants (ZI) offer a good and predictable alternative to reconstructive procedures of atrophic maxillae. The main objetive of this systematic review was to assess the effect of rehabilitation with zygomatic implants on patient's quality of life (QLP) using Patient Reported Outcomes Measures (PROMs).Materials and Methods: This review followed PRISMA guidelines. An automated electronic search was conducted in four databases supplemented by a manual search for relevant articles published until the end of January 2021. The Cochrane Collaboration Risk of Bias tool and the Newcastle-Ottawa Quality Assessment Scale were used to assess the quality of evidence in the studies reviewed.Results: General findings of this systematic review showed substantial increases in Oral health-related quality of life (OHRQoL) among patients restored with ZI and high scores in terms of general satisfaction, especially in chewing ability and esthetics. An overall survival rate of ZI was 98.3% after a mean follow-up time of 46.5 months was observed. Occurrence of 13.1% biological complications and 1.8% technical complications were reported.Conclusions: Patients rehabilitated with zygomatic implant-supported complete dental prostheses showed substantial improvements in OHRQoL and general satisfaction with the treatment received.

Burnout syndrome assessment among Spanish oral surgery consultants: A two populations comparative pilot study

Background: The professional Burnout Syndrome (BOS) or Burnout is considered a professional disease made up of three interrelated dimensions (emotional exhaustion, depersonalization and lack of personal fulfillment). BOS has been documented to most severely affect the healthcare professions, especially dentists. On the other hand, its appearance has been documented at an early age, during dental training. However, there are no studies that analyze its incidence in professionals dedicated to Oral Surgery and Implantology, determining the age of onset and related factors. Material and Methods: The modified Maslach questionnaire was carried out anonymously among the professors and students of the Master of Oral Surgery and Implantology at the Complutense University of Madrid. A total of 36 participants were enrolled in this study and the results of the modified Maslach Questionnaire were established into four groups [1st year (n=6), 2nd year (n=6), 3rd year (n=6) postgraduate students and clinical teachers (n=18)]. The following variables were recorded: Age, sex, years of experience, weekly hours of work, dedication on weekends and scope of work. The statistical analysis performed included Pearson's correlation, analysis of variance, Student's t-test, F-Anova, Chi-Square and Gamma correlation. Statistical Significance of the tests was established of p≤0.05. Results: 36 questionnaires were analyzed, of which 22.2% (n = 8) presented BOS, and 77.8% (n = 28) a medium risk of suffering it. The mean values and standard deviation ​​of emotional exhaustion (7.50 ± 2.43; 9.83 ± 4.12; 15.83 ± 6.21; 30.22 ± 7.86), depersonalization (5.50 ± 1.23; 50 ± 3.27; 11.33 ± 1.75; 17.56 ± 4.13), low personal fulfillment (39.67 ± 3.72; 39.33 ± 2.34; 43.17 ± 3, 55; 37.33 ± 5.51) and professional burnout (54.33 ± 2.66; 61.67 ± 2.88; 70.33 ± 5.43; 85.11 ± 9.05) in the four groups respectively. A significant association was found in the appearance of emotional exhaustion and depersonalization, years of experience, weekly work hours and the work environment. Conclusions: BOS is a disease that can appear from 30 years of age, after 5 years of professional experience and when there is a clinical consultation of 40 hours a week. Oral Surgery and Implantology seems to be a risk activity for the manifestation of depersonalization.(AU)

Management of Schneiderian membrane perforations during maxillary sinus floor augmentation with lateral approach in relation to subsequent implant survival rates: a systematic review and meta-analysis.

BACKGROUND: This systematic review aimed to propose a treatment protocol for repairing intraoperative perforation of the Schneiderian membrane during maxillary sinus floor augmentation (MSFA) procedures with lateral window technique. In turn, to assess subsequent implant survival rates placed below repaired membranes compared with intact membranes and therefore determine whether membrane perforation constitutes a risk factor for implant survival. MATERIAL AND METHODS: This review was conducted according to PRISMA guidelines. Two independent reviewers conducted an electronic search for articles published between 2008 and April 30, 2020, in four databases: (1) The National Library of Medicine (MEDLINE/PubMed) via Ovid; (2) Web of Science (WOS); (3) SCOPUS; and (4) Cochrane Central Register of Controlled Trials (CENTRAL); also, a complementary handsearch was carried out. The Newcastle-Ottawa Quality Assessment Scale was used to assess the quality of evidence in the studies reviewed. RESULTS: Seven articles fulfilled the inclusion criteria and were analyzed. A total of 1598 sinus lift surgeries were included, allowing the placement of 3604 implants. A total of 1115 implants were placed under previously perforated and repaired membranes, obtaining a survival rate of 97.68%, while 2495 implants were placed below sinus membranes that were not damaged during surgery, obtaining a survival rate of 98.88%. The rate of Schneiderian membrane perforation shown in the systematic review was 30.6%. In the articles reviewed, the most widely used technique for repairing perforated membranes was collagen membrane repair. CONCLUSIONS: Schneiderian membrane perforation during MFSA procedures with lateral approach is not a risk factor for dental implant survival (p=0.229; RR 0.977; 95% CI 0.941-1.015). The knowledge of the exact size of the membrane perforation is essential for deciding on the right treatment plan.

Regeneración ósea con injertos intraorales: rama vs. mentón. Puesta al día / Bone regeneration with intraoral graft: ramus vs. chin. Updating

La utilización de injertos intraorales en bloque es una alternativa de tratamiento válida para la regeneración en anchura de defectos óseos maxilares y mandibulares. Sin embargo, actualmente no hay consenso entre los diferentes autores en la elección del mejor tipo de bloque intraoral a utilizar. Por ende, esta puesta al día busca comparar la ganancia ósea, la tasa de complicaciones postoperatorias y el éxito del injerto entre bloques autólogos de rama mandibular y mentón. La ganancia ósea alcanzada es similar en ambos bloques. No obstante, se podría deducir una mayor ganancia al utilizar bloques de la rama mandibular cuando son evaluados mediante CBCT. Además, la tasa de reabsorción ósea fue menor con los injertos de rama. La supervivencia de los implantes es equiparable con ambos tipos de injertos. Las complicaciones que tienen lugar, en orden de frecuencia, son las alteraciones sensoriales, las necrosis pulpares, dehiscencias y hemorragias; apareciendo con mayor frecuencia en los bloques de mentón. Además, el periodo de recuperación en las zonas de rama mandibular es más lento. De este modo, a la hora de la elección parece razonable individualizar el caso y tener en consideración aspectos como la morbilidad y el acceso a la zona donante. (AU)

The use of intraoral block grafts is a valid treatment alternative for the regeneration of maxillary and mandibular horizontal bone defects. However, there is currently no consensus among different authors on the choice of the best type of intraoral bone block to use. Therefore, this update seeks to compare bone gain, post-operative complication rate and grafting success between autologous mandibular ramus and chin bone block grafts. The bone gain achieved is similar in both block grafts. However, a higher gain can be observed by CBCT when using mandibular ramus blocks. In addition, the rate of bone resorption is lower with ramus grafts. Implant survival is comparable in both types of grafts. The complications that occur, in order of frequency, are sensory alterations, pulp necrosis, dehiscence and bleeding, appearing more frequently in chin blocks. In addition, the recovery period in the mandibular ramus areas is slower. Thus, when choosing, it seems reasonable to individualize the case and take into consideration aspects such as morbidity and access to the donor area. (AU)

Split bone block technique: 4-month results of a randomised clinical trial comparing clinical and radiographic outcomes between autogenous and xenogeneic cortical plates.

PURPOSE: To evaluate short-term clinical and radiographic outcomes of bone regeneration procedures using thin cortical porcine xenogeneic bone plates in combination with autogenous bone chips compared with thin autogenous cortical plates and autogenous bone chips. MATERIALS AND METHODS: A total of 19 patients (12 women and 7 men, mean age 58.24 ± 3.09 years) were randomly allocated to two different groups regarding surgical procedure: autogenous cortical plates (ACP group) and xenogeneic cortical plates (XCP group). Preoperative CBCT scans were performed for each patient. Surgical time and postoperative pain were recorded, as well as tissue healing and graft resorption after 4 months, then another surgical procedure was performed to place dental implants. Data were analysed using an analysis of covariance. RESULTS: Twenty-one surgical procedures were performed on 19 patients (10 from the XCP group and 9 from the ACP group). The operative time was significantly lower in the XCP group (25.45 ± 3.88 minutes) than in the ACP group (44.10 ± 3.60 minutes). The XCP group also showed less pain, but not significantly less, than the ACP group. The graft resorption rate in the ACP and XCP groups was 2.03 ± 1.58% and 3.49 ± 2.38% respectively, showing no statistically significant difference. CONCLUSIONS: Despite the limited sample size and non-uniform distribution between the maxilla and mandible as surgical sites, the results suggest that XCP and ACP grafts are similar in terms of bone volume gain and graft resorption rate, with no significant differences in wound healing or complication rate. Nevertheless, the XCP group recorded lower pain levels and required significantly less operative time compared to the ACP group.

Application of propolis extract, nanovitamin C and nanovitamin E to prevent alveolar osteitis after impacted lower third molar surgery. A randomized, double-blind, split-mouth, pilot study / Aplicación de extracto de propóleo, nanovitamina C y nanovitamina E para prevenir la osteítis alveolar después de una cirugía de terceros molares inferiores retenidos. Un estudio piloto aleatorizado, doble ciego y de boca dividida

Background: Propolis has anti-inflammatory, analgesic and healing properties. The purpose of this study was todetermine whether a gel containing 2% of propolis extract, 0.2% of ascorbic acid and 0.2% of tocopherol acetateis effective in preventing surgical complications related to impacted lower third molar extractions.Material and Methods: A randomized, double-blind, split-mouth study was performed. Fifteen patients were re-cruited who needed bilateral impacted lower third molar extractions with a similar surgical difficulty. A test orplacebo gel was administered randomly inside post-extraction sockets. Each patient was instructed to apply thegel 3 times/day in the surgical wound for a week. After a month, the contralateral third molar was extracted, andthe opposite gel applied. The following parameters were diagnosed/evaluated and then recorded: alveolar osteitisfollowing Blum’s criteria, swelling and trismus at day one, two, three and seven post-intervention, wound healingat day 7 post-intervention, and postoperative pain using a visual analog scale, as well as, the number of analgesicpill intake.Results: A total of twenty-six surgical procedures were performed in 13 patients (mean age 20.67±2 years). Alveo-lar osteitis was reported in 3 patients from the placebo group (23.1%) and none in the test group (0%) (p=0.25). Nostatistically significant differences were reported in swelling, trismus, wound healing or analgesic pill consump-tion between two groups. But statistically lower postoperative pain during the 7 days after surgical extractionswas found according to visual analog scale in test group compared to the placebo group (p=0.007). No side effectswere reported.(AU)

Abordaje mediante tres cavidades de un quiste dentígero de gran tamaño: a propósito de un caso / Approach with three cavities of a large dentigerous cyst: a case report

El quiste dentígero se considera un quiste odontogénico del desarrollo que está asociado a la corona de un diente no erupcionado. Suele ser asintomático y carecer de clínica asociada por lo que frecuentemente se trata de un hallazgo casual. Sin embargo puede haber situaciones en los que el quiste afecte a estructuras próximas y/o alcance gran tamaño. Se presenta un caso de un paciente de 65 años que acude derivado por su odontólogo general al constatar la presencia de una lesión radiotransparente de gran tamaño en el cuarto cuadrante. Se realizó un abordaje mediante tres cavidades de la lesión para su completa remoción, así como del cordal incluido asociado a la misma. Por último se colocó una mini placa como refuerzo

The dentigerous cyst is considered an odontogenic developmental cyst that is associated with the crown of a non-erupted tooth. It is usually asymptomatic and has no associated clinic, so it is usually a casual fi nding. However, it can affect nearby structures and / or reach large size. A case of a 65-year-old patient is presented who is referred by his general dentist to verify the presence of a large radiolucent lesion in the fourth quadrant. An approach was made using 3 cavities of the lesion for its complete removal, as well as the included wisdom tooth associated with it. Finally, a mini fi xing plate was placed as reinforcement

Eficacia de los concentrados plaquetarios en distracción ósea alveolar: una revisión de la bibliografía / Efficacy of platelet concentrate application in alveolar distraction osteogenesis technique: a review

INTRODUCCIÓN: La distracción ósea alveolar (DOA), es una técnica de aumento óseo predecible, con resultados exitosos a medio y largo plazo. El uso de concentrados plaquetarios (CP) ha demostrado ser beneficioso en la cicatrización de tejidos blandos y la reparación y regeneración ósea, mediante liberación de factores de crecimiento. Se ha probado el uso de CP durante la distracción de huesos largos, obteniéndose resultados beneficiosos. El objetivo de esta revisión bibliográfica fue analizar los resultados clínicos de la combinación de la DOA y el uso de CP. MATERIAL Y MÉTODO: Se realizó una revisión bibliográfica en tres bases de datos electrónicas sin restricciones. Además, la búsqueda electrónica fue completada con una manual, para identificar cualquier artículo adicional de relevancia. RESULTADOS: Se seleccionaron 6 artículos; dos ensayos clínicos aleatorizados en humanos, dos estudios de experimentación animal y dos casos clínicos. Los artículos incluyeron un total de 27 pacientes y 50 conejos, y utilizaron diferentes protocolos para la obtención de CP. Se registraron ganancias óseas de entre 6,3 mm a 25 mm. Además, tres artículos reportaron complicaciones como parestesia transitoria, infección o inclinación del segmento de transporte. CONCLUSIONES: El uso de CP durante la DOA presenta efectos positivos, disminuir el riesgo de infección y la respuesta inflamatoria, aumentar la vascularización del callo de fractura, producir una aceleración en la regeneración ósea y disminuir el periodo de consolidación. Ante la heterogeneidad de los artículos incluidos, son necesarios más estudios que esclarezcan el papel de los CP y su influencia durante la DOA

INTRODUCTION: Alveolar distraction osteogenesis (ADO) is a predictable bone augmentation technique, with successful results in the medium and long term. The use of platelet concentrates (PC) has been demonstrated to be beneficial in soft tissue healing, in bone repair and regeneration, through the release of growth factors. The use of PC has been used in combination with osteogenesis distraction of long bones, obtaining positive results. The aim of this literature review was to analyze the clinical outcomes of the combination of the alveolar distraction technique and the use of PCs. MATERIAL AND METHODS: A bibliographic review was performed in three electronic databases without time or language restrictions. In addition, the electronic search was completed by a manual, to find any additional relevant articles. RESULTS: 6 articles were selected; two human randomized clinical trials, two animal experimentation and two clinical cases. The articles included a total of 27 patients and 50 rabbits and used different protocols to obtain PCs. Bone gains of between 6.3mm to 25mm were reported. In addition, three articles reported complications such as transient paresthesia, infection, or inclination of the transport segment. CONCLUSIONS: The use of PCs during ADO has positive effects, by decreasing the risk of infection and the inflammatory response, enhancing the vascularization of the fracture callus, causing an acceleration in bone regeneration and reducing the consolidation period. Due the heterogeneity of the articles included, more studies are needed to clarify the role of PCs and their influence during ADO

Classification of sinonasal pathology associated with dental pathology or dental treatment.

BACKGROUND: The pathologies of the posterior teeth in the first and second quadrant and their treatments can be associated with pathology of the maxillary sinus in up to 30% of the cases. Sinus lift surgery in order to place dental implants have increased their incidence. It is necessary, therefore, to address sinonasal pathology (SN) related to dental pathology (DP) or dental treatments (DT) from an interdisciplinary point of view by establishing collaborative working groups between Dentistry (DEN) and Otolaryngology (ENT), as well as by developing registries and establishing coordinated diagnosis and treatment protocols of sinonasal pathology. The aim of this study was to present a brand new and useful classification that relates dental pathology and dental treatments performed on antral teeth with sinonasal pathology to facilitate communication between dentists and otolaryngologists. METHODS: A review of the literature was performed and a classification which related dental pathology and treatments to sinonasal pathology was developed. RESULTS: Six categories are described in our system: absence of sinonasal or dental pathology (0); patients with dental pathology associated (1) or not (4) with sinonasal pathology; 2 and 5- patients with dental treatment not associated (2) or associated (5) with sinonasal pathology; and patients with sinonasal pathology without dental pathology (3). The classification has applications in diagnosis (association and possible causal relationship between the sinonasal and dental pathology) and in the treatment of these pathologies simultaneously or sequentially. CONCLUSIONS: This classification integrates the presence or absence of dental pathology or dental treatment, and its association or not it with sinonasal pathology. Moreover, it facilitates the communication between dentists and otolaringologists and eases the registration of information and the planning of dental, implant and sinus lift treatments.

Effectiveness of the bone ring technique and simultaneous implant placement for vertical ridge augmentation: a systematic review.

BACKGROUND: Dimensional changes after dental extraction frequently lead to situations in which bone augmentation procedures are required prior to dental implant placement. Bone ring technique (BRT) has been described as a one-stage approach to restore vertical alveolar ridge defects, in which an autogenous or allogeneic cortico-cancellous bone block graft is stabilized with a dental implant inserted simultaneously. The objective of this systematic review was to evaluate the clinical performance of BRT. MATERIALS AND METHODS: This review was conducted according to PRISMA guidelines. An electronic search was conducted in four databases: (1) The National Library of Medicine (MEDLINE/PubMed) via Ovid; (2) Web of Science (WOS); (3) SCOPUS; and (4) Cochrane Central Register of Controlled Trials (CENTRAL). The Newcastle-Ottawa Quality Assessment Scale and The Joanna Briggs Institute Critical Appraisal tool were used to assess the quality of evidence in the studies reviewed. RESULTS: Sixteen studies with a total of 186 patients treated with 219 bone rings bocks were included in the review. The studies showed a mean bone gain of 4.94 mm, mean bone resorption of 0.83 mm, and mean marginal bone loss of 0.57 mm after a mean follow-up period of 13.35 months. A mean bone ring survival rate of 97.26% and implant survival rate of 94.97% were recorded. CONCLUSIONS: BRT would appear to be an adequate alternative technique for restoring single vertical alveolar ridge defects with simultaneous dental implant placement. However, further studies comparing this technique with other vertical ridge augmentation procedures in different clinical scenarios are needed to confirm the present results.

Placing Dental Implants through Impacted Teeth to Support a Fixed Partial Denture in a Geriatric Patient as an Alternative to Invasive Extraction Surgeries.

Multiple dental impactions not associated with craniofacial syndromes are a rare condition and present the dentist with a therapeutic challenge when it comes to performing surgical/restorative treatments in adult patients. This case report describes a geriatric patient with multiple impacted teeth restored by means of two different protocols. In the second quadrant, an impacted tooth was extracted followed by regeneration and placement of an implant. In the third quadrant, implants were placed though impacted teeth for restoration with a fixed partial prosthesis. Placing dental implants through impacted teeth may offer a possible therapeutic option for implant-supported restorations in middle-aged or elderly patients, for whom surgery and orthodontic traction are not possible, and/or patients who refuse to undergo more invasive extraction surgery.

Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial

BACKGROUND: The aim of this study was to evaluate and compare the postoperative effect of a topic gel containing chlorhexidine, chitosan, allantoine and dexpanthenol versus a placebo for pain and inflammation control after third molar surgery. MATERIAL AND METHODS: A gel combining 0.2% chlorhexdine, 0.5% chitosan, 5% dexpanthenol, 0.15% allantoin and 0.01% sodium saccharin was selected for this split mouth randomized controlled and double-blind trial including 36 patients with bilaterally and symmetrically impacted lower third molars. The teeth (n = 72) were randomly divided into two groups before surgical removal: control group (CG; in which a placebo was given) and experimental group (EG). Swelling, trismus, postoperative pain, wound healing and complications were measured and recorded in order to evaluate differences between the placebo and experimental product. RESULTS: Five patients suffered from an alveolitis in the CG (13.9%), and none in the study group (0%), but no statistically significant difference was found (p = 0.063). From day 0 to day 7, trismus and swelling were significantly less pronounced in the EG, and wound healing was considered 'good' in 22.2% for the CG and 97.2% for the EG (p < 0.001). Mean VAS scores during the seven postoperative days were statistically lower in the study (2.56 ± 1,19) compared to the placebo group (3.25 ± 1.6) (p = 0.002). The mean consumption of analgesic pills during the first 92 hours was also statistically lower in the EG (0.26 ± 0.51) in comparison to the CG (0.56 ± 0.67) (p = 0.003). CONCLUSIONS: The use of an experimental gel containing chlorhexidine, chitosan, allantoine and dexpanthenol seems to significantly reduce postoperative pain, trismus and signs of inflammation. Future studies should further evaluate, if the gel is effective in dry socket preventing after third molar removal

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Material de injerto en elevación de seno atraumática: ¿es necesario? Parte I / Graft material in atraumatic sinus lift elevation: ¿is it necessary? Part I

INTRODUCCIÓN: la reabsorción vertical de la zona posterior del maxilar supone un reto terapéutico para el profesional, ya que son necesarias técnicas regenerativas para poder colocar implantes den-tales. La elevación de seno atraumática permite la colocación de implantes dentales de manera simultánea al procedimiento regenerativo, pero hay controversia en la necesidad o no de emplear materiales de injerto asociados a esta técnica. Ganancia ósea: al comparar la utilización o no de materiales de injerto en elevaciones de seno atraumáticas, se obtiene una ganancia ósea de 1-6.8 mm cuando no se emplean biomateriales, y 3.07-8.5 mm al utilizarlos. Pérdida ósea marginal: los estudios reflejan una pérdida ósea marginal de 0.5-1.54 mm al no emplear materiales de injerto, respecto a 0.7-1.67 mm cuando se utilizan. Supervivencia de implantes: ambas técnicas de elevación de seno atraumática presentan tasas de supervivencia imlantarias similares, superiores al 90 %.Complicaciones: la tasa de complicaciones en esta técnica regenerativa es baja, siendo la más frecuente la perforación de la membrana de Schneider, no suponiendo en la mayoría de los casos un impedimento para la colocación de implantes dentales. CONCLUSIONES: la técnica de elevación de seno sin relleno presenta menor ganancia ósea y pérdida ósea marginal en comparación a la técnica de elevación de seno con relleno, pero ambas técnicas presentan tasas de supervivencia implantarias similares, y una baja tasa de complicaciones, por lo que la utilización o no de biomateriales asociados debe decidirse en función de todas estas variables

INTRODUCTION: vertical resorption of posterior maxilla is a therapeutic challenge for dentists, since regenerative techniques are necessary to be able to place dental implants. Atraumatic sinus lift augmentation allows simultaneous dental implants placement to regenerative procedure, but it is not clear nowadays if it is or not necessary to use associated graft materials. Bone gain: scientific evidence reports a bone gain of 1-6.8 mm without using graft materials, versus 3.07-8.5 mm when authors use graft materials in atraumatic sinus lift augmentations procedures. Marginal bone loss: similar bone loss is expected in both techniques, but atraumatic sinus lift augmentation presents 0.5-1.54 mm when graft material is not used, versus 0.7-1.67 mm when graft material is used. Implant survival: both techniques present similar survival implant rates, greater than 90 %.Complications: low complications rate is reported, being the most frequent complication Schneider membrane perforation. Nevertheless, dental implant placement is possible in spite of this complication. CONCLUSIONS: atraumatic sinus lifting without graft materials presents lower bone gain and marginal bone loss in comparison to atraumatic sinus lifting with graft materials. Both techniques present similar survival implant rates and low complication rates, so using or not grafting materials should be decided analyzing all these variables

Autogenous Dentin Graft in Bone Defects after Lower Third Molar Extraction: A Split-Mouth Clinical Trial.

Various biomaterials are currently used for bone regeneration, with autogenous bone being considered the gold standard material because of its osteogenic, osteoconductive, and osteoinductive properties. In recent years, the use of autogenous dentin as a graft material has been described. This split-mouth clinical trial assesses the efficacy of autogenous dentin for the regeneration of periodontal defects caused by bone loss associated with impacted lower third molar extraction. Fifteen patients underwent bilateral extraction surgery (30 third molars) using dentin as a graft material on the test side, and leaving the control side to heal spontaneously, comparing the evolution of the defects by evaluating probing depth at three and six months post-operatively. Bone density and alveolar bone crest maintenance were also evaluated six months after surgery, and pain, inflammation, mouth opening capacity on the second and seventh days after surgery. Probing depth, radiographic bone density, and alveolar bone crest maintenance showed significant differences between the test and control sides. Autogenous dentin was found to be an effective biomaterial for bone regeneration after impacted lower third molar extraction.

Effects of locally applied Insulin-like Growth Factor-I on osseointegration

Background: The aim of this study was to assess the effect of local application of IGF-I on osseointegration of dental implants placed in osteoporotic bones. Material and Methods: 16 rabbits were randomly distributed into two groups: eight animals were ovariectomized and fed a low-calcium diet for six weeks, in order to induce experimental osteoporosis, and the others were sham-operated and fed a standard diet. A titanium implant was inserted into the tibiae in both groups. In half of the rabbits, 4 μg of IGF-I was applied into the ostectomy, prior to the implant insertion. A total of 32 implants were placed. Animals were sacrificed two weeks after surgery and decalcified samples were processed for Bone-To-Implant Contact (BIC) and Bone Area Density (BAD) measurements. Analysis of variance (ANOVA) was used for statistical evaluation. P < 0.05 was considered to be significant. Results: Ovariectomy induced statistically significant lower BAD values (p = 0.008) and a tendency towards lower BIC values when compared osteoporotic and healthy groups. The administration of 4 μg of IGF-I did not produce statistically significant differences neither on BIC nor on BAD values, neither in the osteoporotic animals nor in healthy. Conclusions: Within the limitations of this experimental study, local administration of 4 μg of IGF-I was not able to induce any changes in the osseointegration process two weeks after surgery, neither in healthy rabbits nor in the osteoporotic group

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Tratamiento del tumor odontogénico queratoquístico: revisión sistemática / Surgical treatment of odontogenic keratocystic tumor: a systematic review

Introducción: El queratoquiste odontogénico (QO) se considera hoy en día un tumor odontogénico benigno. A pesar de esto, tiene un carácter agresivo debido fundamentalmente a su potencial expansivo a nivel local y a su alta capacidad de recidiva. Actualmente, existen diferentes variedades terapéuticas que se relacionan directamente con las tasas de recurrencia de este tipo de tumor. Objetivo: El objetivo de este estudio es analizar las tasas de recurrencia de las diferentes modalidades de tratamiento del QO. Material y método: Siguiendo las recomendaciones PRISMA se realizó una revisión sistemática en diferentes bases de datos analizando las tasas de recurrencia de distintas opciones terapéuticas del QO. Resultados: El porcentaje medio de recurrencia de los 11 artículos revisados fue del 26,8 %, siendo la resección en bloque el tratamiento con menores tasas de recidiva (0 %) y la marsupialización el tratamiento que mayor porcentaje de recurrencia presentó (45,8 %). Discusión: La recidiva se relaciona directamente con la posibilidad de que restos del tumor o del epitelio que lo rodea puedan permanecer en la cavidad después del tratamiento. Por ello, la resección en bloque es el tratamiento que menos recurrencia presenta. Sin embargo, la agresividad de esta modalidad terapéutica no está justificada en todos los casos, existiendo otras variantes muy eficaces como la enucleación, ya sea sola o en combinación con terapias coadyuvantes como la aplicación de solución de Carnoy. Conclusiones: El tratamiento resectivo presenta las menores tasas de recurrencia, aunque se considera que el QO puede ser abordado de una manera más conservadora dada su naturaleza benigna

Introduction: The odontogenic keratocystic (OK) is considered nowadays as a benign odontogenic tumor. Nevertheless, it has an aggressive nature due mainly to its local expansive potential and its high recurrence rate. Currently, there are different therapeutic approaches that are directly related to the recurrence rates of this type of tumor. Objective: The objective of this study is to analyze the recurrence rates of the different treatment modalities of the OK. Material and method: Following PRISMA recommendations, it was perfomed a systematic review in different databases analyzing the recurrence rates of different therapeutic options of the OK. Results: The average percentage of recurrence of the 11 articles reviewed was of 26,8 %, being resection the treatment with lower recurrence rates (0 %) and marsupialization the treatment with the highest percentage of recurrence (45,8 %). Discussion: Recurrence is directly related to the possibility that parts of the epithelium may remain in the cavity after treatment. Therefore, resection is the treatment with the least recurrence. However, the aggressiveness of this therapeutic modality is not justified in all cases. There are other very effective variants such as enucleation either alone or in combination with adjuvant therapies such as Carnoy's solution application. Conclusions: Resective treatment has the lowest recurrence rates although it is considered that the OK can be approached in a more conservative way due to its benign nature

Aumento de tejido blando peri-implantario. ¿Qué momento temporal y técnica quirúrgica debo emplear para conseguir que mis resultados sean predecibles? Revisión de la literatura / Peri-implant soft tissue augmentation. The suitable moment and surgery technique to predict optimum success. A review of the literature

El papel de una anchura adecuada de mucosa queratinizada (MQ) alrededor de los implantes dentales en la estabilidad a largo plazo de los tejidos periimplantarios sigue siendo un tema de debate. El objetivo de esta revisión fue evaluar y describir los resultados sobre las técnicas quirúrgicas disponibles y el momento temporal en el que llevar a cabo el incremento de los tejidos blandos periimplantarios. Para ello se realizó una búsqueda bibliográfica electrónica en las bases de datos PubMed y Medline, y manual de artículos relevantes, considerando el período entre 2012 y 2017 e incluyendo aquellos artículos que trataban sobre diferentes técnicas quirúrgicas realizadas a partir del momento temporal B (desde la colocación de los implantes). Se incluyeron un total de 10 artículos, comparándolos en función del momento temporal en el que se realizó la técnica quirúrgica y analizando las siguientes variables de estudio: anchura de mucosa queratinizada, grosor/espesor de mucosa queratinizada, contracción postoperatoria, tiempo quirúrgico y estética y disconfort postoperatorio. Se puede concluir que el injerto gingival libre ha demostrado obtener las mayores anchuras de mucosa queratinizada. No obstante, existen otros materiales disponibles que reducen la morbilidad del paciente y evitan un segundo sitio quirúrgico como la matriz de colágeno xenogénica que podría ser tan efectiva y predecible como éste. Tanto la matriz de colágeno xenogénica como el injerto de tejido conectivo ofrecen resultados estéticos superiores a los conseguidos con el injerto gingival libre

The role of an adequate width of keratinized mucosa (KM) around dental implants in the long-term stability of peri-implant tissues is still controversial. The aim of this study was to evaluate and describe the results of the surgical techniques available and the moment in which the increase of the peri-implant soft tissues should take place. An electronic bibliographic search was carried out in the PubMed and Medline databases, considering the period between 2012 and 2017 and including those articles that dealt with different surgical techniques performed from time B (from the implants fitting). A total of 10 articles were included, comparing them according to the time when the surgical technique was performed and analyzing the following study variables: width of keratinized mucosa, thickness of keratinized mucosa, postoperative contraction, surgical and aesthetic time and postoperative discomfort. It can be concluded that the free gingival graft has been shown to obtain the largest widths of keratinized mucosa. However, there are other materials available that reduce the morbidity of the patient and avoid a second surgical site such as the xenogeneic collagen matrix which can be as effective and predictable as the free gingival graft. Both the xenogeneic collagen matrix and the connective tissue graft offer superior aesthetic results to those obtained with the free gingival graft